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Accenture’s Barry Heavey discusses how the life sciences industry has changed and the most in-demand roles and skills right now.

At the end of last year, data from pharma recruiter Cpl Life Sciences and data analytics company Vacancysoft revealed that there was record recruitment in Ireland’s life sciences sector in 2021.

This year has already seen expansion across a number of pharma, biotech and medtech companies in Ireland, including Boston Scientific, Medtronic, Janssen and Merck.

So for those looking to work in the sector, what are the most in-demand roles right now and what skills do they need to be successful in the industry?

Barry Heavey is the managing director of life sciences at Accenture in Ireland. He told SiliconRepublic.com that he is seeing a lot of demand for skills in digital technology right now.

“What we look for is people who can combine skills in digital technologies with an understanding of the actual problems and complexities that companies face in developing and supplying ever more complex products to ever-more focused patient populations,” he said.

“Across the wider industry in Ireland, I see a very large demand for people who are interested in working in manufacturing, quality, supply chain management, regulatory affairs, data analytics and process development.”

While some graduates with a science degree might not see a role in manufacturing or quality as an exciting long-term option compared to R&D, Heavey said it’s important not to discount these career paths.

“Most biopharma companies need their manufacturing and quality teams to orient themselves more towards development and research, so these roles will hold exciting development opportunities while giving new graduates a great first step on the career ladder where they can learn all about the challenges of producing highly complex products to save lives.”

While there are a wide range of technical skills that will be needed in life sciences such as mRNA synthesis and formulation, conjugation chemistry, multivariate analysis, and artificial intelligence, Heavey said “multi-disciplinarity is key”.

“We need manufacturing and quality people who can collaborate with R&D and regulatory affairs people and vice versa. We need people who combine scientific, engineering, IT and business skills as well as the wider skills of communication, storytelling, project management, etc.”

Heavey also said that the industry is moving so fast now that the old siloed ways of working are no longer viable. Even though deep expertise in specific areas is required, collaboration is vital.

“Digital tools can be a key enabler of better collaboration, and innovation like advanced data analytics and artificial intelligence can also help in surfacing insights and enabling better decision-making using technology and curating and sharing knowledge over time and between teams.”

Biggest trends in the industry

For those working in the sector, one of the biggest trends is around new ‘modalities’ – new modes of treatment such as conjugated proteins, mRNA and cell therapy.

“We had the explosion of the new modality of recombinant proteins over the past 20 years, but this modality is represented by some of the best-selling drugs in the world like Keytruda, Humira, etc. and Ireland is central to the supply of these products due to proactive targeting of investment by the IDA and training capabilities from organisations such as NIBRT,” said Heavey.

He added that while Ireland was able to capitalise on the growth of the recombinant protein modality the country needs to ensure “we catch the next waves of the next generation of modalities”.

“We are seeing progress in this with Pfizer making their mRNA vaccine for Covid in their Dublin facility, but we need to continue to watch for new opportunities and invest in training our workforce to be ready for these.”

Another big trend is the increased pace of innovation. The timeframe of 10-15 years to approve a newly discovered drug has been drastically compressed in recent years. Most recently, the world saw several Covid-19 vaccines approved in under one year.

Heavey said this increased pace is partly due to the new modalities but also due to the better collection and use of data.

“With the pace of innovation in digital and medical technology, we now have the data collection and analysis tools needed to understand disease in more depth, to develop and even design new drugs faster, to decide what patients might be most likely to benefit from a treatment and to determine whether the drug is effective and safe in patients with much higher fidelity,” he said.

For those entering the industry, Heavey advised them to “think about the white space between disciplines”.

“If you are strong in digital technologies, think about upskilling in areas like biotechnology or medical device technology, so you can speak the language of people who need your IT skills.  If you are strong in R&D, think about how you can collaborate more effectively with people in manufacturing who will be trying to put new modalities on the shelves.

“If you are strong in quality control, think about what is coming next from R&D (new modalities or new analytical methods) and how you can prepare for these and expedite their introduction through enhanced collaboration,” he said.

“Bottom line is never stop learning! It is such an exciting industry to be in and I, for one, feel privileged to be involved in it.”

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Google UK staff earned average of more than £385,000 each in 18 months | Google

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Google UK’s staff earned an average of more than £385,000 each in the 18 months to the end of December, as the tech company gave almost £1bn in share-based payments.

Google, which like other tech firms is looking at budget and potential job cuts as global economic conditions become tougher, reported £3.4bn in turnover and £1.1bn in pre-tax profits in the 18 months to the end of December 2021.

The company, which reported a year and a half of financial results after moving its accounting period from the end of June to December last year, paid £200m in UK corporation tax.

Google UK hired 577 staff between June 2020 and December last year, taking its total headcount to 5,701. The company employs 2,275 staff in sales and marketing roles, 2,412 in research and design and 1,014 in management and administration roles.

Google’s total staff costs hit £2.2bn in the 18-month reporting period, according to accounts filed at Companies House. The staff wage and salary bill came to £1.06bn.

The accounts show UK staff received an £829m bonanza in share-based payments, and there was £258m on social security costs and £52m in expenses relating to its defined contribution plan.

The accounts also show that Google paid £200m in UK corporation tax on its £1.1bn profits.

Like its tech peers Meta – the owner of Facebook and Instagram – and Amazon, Google is frequently the target of criticism that it does not pay enough in tax in the UK.

While the company reported £3.4bn in turnover over its 18-month reporting period, the research firm Insider Intelligence estimates that Google made almost £8.7bn in ad revenue in the UK in 2021 alone.

Google, which has its European headquarters in Ireland, where taxes are lower, reports some revenues in other jurisdictions.

“Our global effective income tax rate over the past decade has been close to 20% of our profits, in line with average statutory tax rates,” a spokesperson for Google said. “We have long supported efforts via the OECD [Organisation for Economic Co-operation and Development] to update international tax rules to arrive at a system where more taxing rights are allocated to countries where products and services are consumed.”

In November, Google’s Irish subsidiary agreed to pay €218m (£183m) in back taxes to the Irish government. In 2020, Alphabet, Google’s parent company, said it would stop using a notorious tax loophole known as “the double Irish with a Dutch sandwich”.

In 2020, the UK introduced a digital services tax, which levies 2% of gross revenues, and aimed to target large digital companies that make huge revenues but report relatively small profits.

Next year, it will be replaced by a new global tax system after the OECD brokered a deal between 136 countries that will result in large multinational companies paying tax in the countries where they do business, and committing themselves to a minimum 15% corporation tax rate.

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Tesla has a bit of work to do on Optimus robot • The Register

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Tesla headlined its AI Day 2022 event on Friday with the reveal of its “Optimus” robot prototype, showing just how much work was left to do on the project.

While the demo was certainly more robotic than last year’s dancer in a onesie, the lumbering mess of cables was far from the sleek and sexy design faithful Muskites might expect from the EV maker.

CEO and founder Elon Musk said before the curtains opened: “I do want to set some expectations with respect to our Optimus robot. As you know, last year it was just a person in a robot suit, but we’ve come a long way and, you know, compared to that, it’s going to be impressive.”

But in a world accustomed to the back-flipping bots of Boston Dynamics, Optimus was less than impressive. A mechanical engineer stepped in to inform the audience that this was the first time the robot was run “without any backup support – cranes, mechanical mechanisms, no cables, nothing.”

Tesla Optimus protoype

Tesla’s ‘rough development robot’

The prototype managed to rotate its arms, then tottered to the forefront to give the audience a wave, before walking back as a screen failed to close. “This is essentially the same self-driving computer that runs in Tesla cars by the way,” an Autopilot engineer proclaimed.

The event then showed videos of the robot picking up and putting down objects, and watering plants. “What you saw … was our rough development robot using semi-off-the-shelf actuators. But … we actually have an Optimus bot with fully Tesla-designed and built actuators, battery pack, control system, everything.”

This version, which was then pushed onto the stage, was a little more “Tesla” – slimmer, neater, shinier. Only one problem: it can’t walk. “I think it will walk in a few weeks,” Musk said, “but we wanted to show you something that’s fairly close to what will go into production.”

Clumsily wheeled out by staff, it also managed a couple more waves and did the splits from the rod on which it was mounted.

“Our goal is to make a useful humanoid robot as quickly as possible,” Musk said. “We’ve also designed it using the same discipline we use in designing the car, which is to say to design a form of manufacturing such that it is possible to make the robot in high volume at low cost with higher liability.

“You’ve all seen very impressive humanoid robots demonstrations, and that’s great, but what are they missing? They’re missing a brain. They don’t have the intelligence to navigate the world by themselves. They’re also very expensive and made in low volume. Optimus is designed to be an extremely capable robot but made in very high volume – ultimately millions of units – and it’s expected to cost much less than a car, so probably less than $20,000.”

That’s one expensive Roomba.

Accepting that there was “a lot of work to be done to refine Optimus and improve it,” Musk said the aim of the event was convince more AI and mechanical engineers to join the company to bring the project “to fruition at scale” and “help millions of people.”

He then waxed lyrical about an economy where there was “not a limitation on capita,” which could then become “quasi-infinite,” implying that he hopes Tesla’s robots might one day replace humans on production lines.

“This means a future of abundance,” he said. “A future where there is no poverty, where you can have whatever you want in terms of products and services. It really is a fundamental transformation of civilization as we know it.”

As if to reference his belief that AI is humanity’s “biggest existential threat,” he added: “Obviously, we want to make sure that transformation is a positive one and safe,” claiming that Tesla’s public ownership model was the right way to achieve this.

While not quite the disasterpiece of the Cybertruck reveal, going by what was shown at the AI Day, such a utopia is still far away. ®

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Dublin proptech constructing an operating system for buildings

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The SpaceOS platform sets out to create smart workplaces as the world wises up to the future of hybrid, flexible and sustainable work.

“We believe that buildings have been failing to answer people’s needs for decades,” said Marley Fabisiewicz. “We’re making them more convenient and human-centric with technology, while feeding the property managers and real estate developers with data.”

That, in a nutshell, is what proptech start-up SpaceOS is all about. “The real estate industry is a dinosaur,” said co-CEO Fabisiewicz, whose vision is to realise its digital transformation through developing tech-enabled workspaces. “Our mission is to help companies attract, retain, inspire and empower their people by creating dynamic and digitised workplace communities.”

Headquartered in Dublin, SpaceOS offers a workplace experience platform that Fabisiewicz said “turns smartphones into remote controls for the workplace”. The name derives from the concept of creating “an operating system for buildings”.

What this involves, Fabisiewicz explained, is digitising physical assets and providing APIs to integrate existing business technologies, such as access control. “[SpaceOS] covers everything from opening doors and booking desks and rooms, to ordering food, registering guests and sending out invoices, all blended seamlessly into daily workflows,” he said.

“Because of its modular structure, SpaceOS is ready to integrate with a variety of platforms to meet the specific requirements of any workspace infrastructure. It connects all stakeholders, reduces inputs and costs, provides insights, and offers smart management tools. It provides building managers and users with transparency, cost efficiency and real-time information, while focusing on the user experience.”

‘Dynamic workspaces are shaping the future of work’
– MARLEY FABISIEWICZ

Fabisiewicz sees the platform as essential to the transformed modern workplace. “We are targeting building owners, tenants, and managers. With a high demand for spaces to fit varying needs in a modern work environment, dynamic workspaces are shaping the future of work,” he said.

“However, current building management tools were typically designed before hybrid working became mainstream. As a result, they are inflexible and lack the adaptability and technology necessary to make today’s workspaces more efficient, while reducing operating costs.”

Demand for SpaceOS could also be employee-driven, Fabisiewicz explained, as modern workers demand systems that enable flexibility, engagement and sustainable practices. Clients can use the platform to deliver push notifications for news, events or community updates, and the service also offers detail data on carbon emissions, to support net-zero initiatives.

Environmental, social, and governance (ESG) goals have been a focal point of the start-up in the past year, leading to a partnership with Germany company Aedifion, which provides a cloud-based platform to collate data on buildings’ energy consumption.

“This collaboration allows property owners and managers to offer tenants a real-time visualisation of metrics regarding their energy usage and carbon emissions. This is the basis for transparency, and a step to make everyone in the workplace become a sustainability activist, supporting the decarbonisation of buildings,” said Fabisiewicz.

“We are currently working on managing heating, ventilation and energy based on occupancy and capacity data, to decarbonise buildings even more effectively. Future integrations will also allow tenants to remote-control HVAC, blinds, lights and more, through the SpaceOS app.”

‘The landscape has changed significantly since the markets tanked’
– MARLEY FABISIEWICZ

Serial entrepreneur Fabisiewicz also founded Upnext Technologies, a software and digital product development agency focused on the fintech industry.

SpaceOS was founded in 2017 by Fabisiewicz and his co-CEO Maciej Markowski, who has a background in real estate consultancy and proptech. “He has international experience in corporate workplace and change issues, advising major corporations on their workplace research, strategy and change management,” said Fabisiewicz.

So far, the founding duo have increased revenue three times over in the past 12 months and built up a strong client portfolio. “However, we are still in the early innings of the proptech game,” said Fabisiewicz. “Market saturation for tenant experience technology is at around 5pc globally, so there’s still a massive upside potential and room to grow.”

Of course, the present-day market disruptions present a challenging environment for growth and investment. “The landscape has changed significantly since the markets tanked,” said Fabisiewicz. “12 months ago, it was all about hypergrowth. Today, it’s all about how quickly you can become profitable.”

In Dublin, however, Fabisiewicz describes the start-up ecosystem as “a continuous boom” with “more money to be deployed by investors, more founders with great ideas, and a maturing ecosystem for start-ups in general”.

In his company’s case, SpaceOS is looking for “smart money” that offers more than a cash injection. Fabisiewicz is seeking investors who “not only write a cheque, but also support in building the business”.

“I believe especially in proptech this is essential for a successful start-up,” he said.

10 things you need to know direct to your inbox every weekday. Sign up for the Daily Brief, Silicon Republic’s digest of essential sci-tech news.

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